The American Association for Klinefelter Syndrome Information & Support is a 501(c)(3) nonprofit organization

The American Association for Klinefelter Syndrome Information and Support (AAKSIS) is a national volunteer association with the mission of education, support, research, and understanding of 47,XXY, and its variants, collectively known as Klinefelter syndrome.

AAKSIS is governed by a Board of Directors and is assisted by a Professional Advisory Board.

AAKSIS is dedicated to bringing you accurate and current information about Klinefelter Syndrome and is a network for individuals, families, and anyone interested in learning more about Klinefelter Syndrome.

Klinefelter Syndrome, 47,XXY, is one of the most common of sex chromosome variations, and is said to occur in approximately 1 out of 500-750 males. Statistics suggest that there are thousands of 47,XXY individuals in the United States alone. Many remain undiagnosed.

Current and accurate information about 47,XXY required by those confronted with a new diagnosis is often hard to find.